The Tolia Laboratory study the pathogenesis of infectious disease.

We use the tools of structural biology, biochemistry, biophysics, microbiology and parasitology to examine proteins and protein complexes associated with pathogenesis.

One major research interest is red blood cell invasion by Plasmodium parasites. Malaria causes an estimated 300-500 million cases and 1-3 million deaths annually, 80% of which are in children under the age of five. The clinical symptoms of malaria occur upon red blood cell invasion by Plasmodium parasites, the causitive agents of the disease. Therefore, recognition and invasion of red blood cells is an attractive target for therapeutics and an active area of research.

A postdoctoral research fellow position is available
Undergraduate research opportunities