wumsMM (28K) Department of Molecular Microbiology, Washington University School of Medicine

Tolia Laboratory


Introduction

Publications

Who We Are

Contact Us
Publications

Tolia NH, Joshua-Tor L. “Slicer and the Argonautes” Nature Chemical Biology (2007) Jan;3(1):36-43.

Yigit E, Batista PJ, Bei Y, Pang KM, Chen CG, Tolia NH, Joshua-Tor L, Mitani S, Simard MJ, Mello CC. “Analysis of the C. elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi” Cell (2006) Nov 17;127(4):747-757.

Irvine DV*, Zaratiegui M*, Tolia NH*, Goto DB, Chitwood DH, Vaughn MW, Joshua-Tor L, Martienssen RA “Argonaute slicing is required for heterochromatic silencing and spreading.” Science (2006) Aug 25; 313(5790):1134-7.
*co-first authors

Tolia NH§, Joshua-Tor L. “Strategies for protein coexpression in Escherichia coli.” Nature Methods (2006) Jan; 3(1):55-64
§corresponding author

Tolia NH, Enemark EJ, Sim BKL, Joshua-Tor L. “Structural basis for the EBA-175 erythrocyte invasion pathway of the malaria parasite P. falciparum.” Cell (2005) Jul 29; 122(2):183-93

Rivas FV*, Tolia NH*, Song JJ*, Aragon JP, Liu J, Hannon GJ, Joshua-Tor L. “Purified Argonaute2 and an siRNA form recombinant human RISC.” Nature Structural & Molecular Biology (2005) Apr; 12(4):340-9. Epub Mar 30.
*co-first authors

Song JJ, Liu J, Tolia NH, Schneiderman J, Smith SK, Martienssen RA, Hannon GJ, Joshua-Tor L. “The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes.” Nature Structural Biology (2003) Dec; 10(12):1026-32. Epub Nov 16.