Introduction
The Tolia lab study the molecular events that occur during erythrocyte invasion by Plasmodium parasites. We use the tools of structural biology and biochemistry to examine proteins and protein complexes associated with these events.
Malaria causes an estimated 300-500 million cases and 1-3 million deaths annually, 80% of which are in children under the age of five. The clinical symptoms of malaria culminate upon red blood cell invasion by Plasmodium parasites, the etiological agents of Malaria. Therefore, preventing binding and invasion of the red blood cells is an attractive target for therapeutics.
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Who We Are
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Niraj H. Tolia, PhD Assistant Professor of Molecular Microbiology and Biochemistry and Molecular Biophysics E-mail: tolia@wustl.edu |
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| Present Position | |
| 2007 - present | Assistant Professor, Departments of Molecular Microbiology and Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, USA |
| Education | |
| 1999 - 2004 | Ph. D. Biological Sciences, Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA |
| 1995 - 1999 | B.Sc. Biochemistry, Imperial College of Science, Technology and Medicine, London, UK. |
| Professional Experience and Appointments | |
| 2007 - present | Assistant Professor, Departments of Molecular Microbiology and Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, USA |
| 2004 - 2007 | Postdoctoral Fellow, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA |
| 1997 - 1998 | Industrial Trainee, Drug Metabolism Department, Pfizer Central Research, Sandwich, Kent, UK |
| University Appointments and Committees | |
| 2008 - present | PhD Admissions Committee, The Division of Biology and Biomedical Sciences, Washington University, St. Louis, MO, USA |
| Fellowships and Awards | |
| 2006 | Malaria: Functional Genomics to Biology to Medicine Meeting Scholarship, Keystone Symposia |
| 1999-2004 | Leslie Quick, Jr. Fellowship, Watson School of Biological Sciences |
| 1999-2004 | C. Ewart Stickings Memorial Prize. Distinction award from the Department of Biochemistry, Imperial College |
| 1998 | IMPACT Award, Pfizer Central Research award for innovation |
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Jacob Zahm Research Technician II |
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Nichole Salinas Graduate Student |
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Dan Lin Undergraduate Student |
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Aditya Radhakrishnan Undergraduate Student |